Laser: a powerful tool for photoacoustic and fluorescence imaging
Laser has shone brightly in the field of biomedical imaging, especially playing a key role in photoacoustic imaging and fluorescence imaging.
In photoacoustic imaging, a pulsed laser is the core excitation source. When the laser beam emitted by it irradiates biological tissue, the tissue absorbs energy and undergoes thermal expansion due to instantaneous temperature changes, thereby generating photoacoustic signals. These signals carry the light absorption characteristics of tissues, and through detection and reconstruction algorithms, high-resolution images reflecting tissue structure and function can be generated. Photoacoustic imaging combines the advantages of optics and ultrasound imaging, with deeper penetration than pure optical imaging and higher resolution than traditional imaging techniques. It has shown great potential in early cancer diagnosis, organ oxygen supply detection, and other fields.
Fluorescence imaging utilizes laser excitation of fluorescent groups to produce fluorescence for imaging. The high brightness and directionality of the laser ensure efficient fluorescence excitation, reduce non target wavelength interference, and improve signal-to-noise ratio. Confocal microscopy imaging technology is developed based on this, which uses fluorescence microscopy to observe the fluorescence of biological samples, removes the influence of stray light through point-to-point scanning, has higher axial resolution, can obtain continuous optical sections, increases lateral resolution, and is widely used in cell biology and clinical diagnosis.
Laser has brought many advantages to photoacoustic imaging and fluorescence imaging, improving imaging quality, expanding functional boundaries, and increasing experimental flexibility. With the development of technology, RealLight’s laser brings many advantages to photoacoustic imaging and fluorescence imaging, and will continue to emit light and heat in the biomedical field in the future.
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