Pulsed lasers serve as the core light source for photoacoustic imaging (PAI), enabling high-resolution and high-contrast biological tissue imaging due to their high peak power and ultrashort pulse characteristics. This article reviews the evolution of the photoacoustic effect from Bell's era to modern laser technology, with a focus on the advantages of pulsed lasers (e.g., Nd:YAG and microchip lasers) in vascular imaging, tumor detection, and brain science research. Studies show that the nanosecond-level short pulses and compact design of microchip lasers make portable PAI devices feasible. In the future, with advancements in laser technology and algorithms, the clinical applications of pulsed lasers in PAI will expand further.

Lasers are the core component of photoacoustic imaging (PAI), directly determining image quality. This article examines the operational principles of lasers in PAI, compares traditional nanosecond lasers (e.g., Nd:YAG/OPO) with modern compact lasers (e.g., RealLight’s MCA/MCC series), and analyzes how wavelength selection balances resolution and penetration depth. The study highlights that advancements in laser miniaturization and high repetition rates will further expand PAI’s applications in clinical diagnosis and biomedical research.

Narrow-linewidth lasers significantly enhance Raman spectroscopy by providing high spectral purity, wavelength stability, and sufficient power, improving measurement accuracy and signal-to-noise ratio. These lasers enable high-resolution spectral analysis in biomedical diagnostics (e.g., cancer detection), pharmaceutical quality control, and material science. They are particularly valuable for low-wavenumber Raman measurements and high-resolution imaging, such as cellular and molecular mapping. With their ability to reduce background noise and support precise wavelength control, narrow-linewidth lasers expand Raman spectroscopy’s applications in research and industry. As technology advances, their adoption is expected to grow, driving innovations in scientific and medical diagnostics.

RealLight’s 1535nm eye-safe laser is designed for radar and laser ranging, combining high performance with operational safety. Its wavelength meets eye safety standards, while its exceptional stability ensures reliable measurements in harsh environments. With competitive cost-efficiency, the laser reduces procurement and maintenance expenses through optimized manufacturing. Suitable for both (radar detection) and civilian (distance measurement) applications, the 1535nm laser delivers long-range, high-precision performance. A perfect blend of quality and affordability, it stands as an ideal choice for professional ranging solutions.

Since its introduction in the 1960s, Laser-Induced Breakdown Spectroscopy (LIBS) has been widely applied in fields such as metal analysis, environmental monitoring, and cultural heritage identification. LIBS operates by using an ultrashort pulse laser to ablate a sample, generating plasma, and then analyzing its spectral emissions to determine elemental composition. The excitation source and spectral acquisition system are the core components of LIBS, with high peak power ultrashort pulse lasers being particularly crucial. RealLight has independently developed the PQE series solid-state lasers, which utilize passive Q-switching technology. These lasers feature high energy output, low power consumption, and a compact design, making them ideal for handheld, portable, and online LIBS systems, enhancing precision detection and analysis.

In the field of medical aesthetics, Nd:YAG lasers are widely used for pigment removal, and pulse width selection directly affects treatment outcomes. Compared to nanosecond Q-switched lasers, picosecond lasers offer superior pigment fragmentation and a more comfortable treatment experience, with the stability of the seed source being a critical factor. RealLight’s MCD series microchip picosecond seed sources provide high pulse energy, excellent beam quality, and selectable pulse widths, offering a high-performance and stable laser solution for medical aesthetic applications.

Picosecond lamp-pumped lasers utilize high-energy laser pulses with extremely short durations to precisely treat target objects through biological fragmentation. In the field of medical aesthetics, they are primarily used to destroy melanocytes, break down pigmentation, and improve uneven skin tone, enabling personalized beauty solutions such as laser pigmentation removal, hair removal, and skin rejuvenation. RealLight's independently developed HQF lamp-pumped MOPA picosecond laser uses the MCD series microchip laser as the seed source, combined with a lamp-pumped laser amplifier. It features high energy, narrow pulse width (300ps~2ns), strong stability, and uniform beam quality, with wavelengths covering 1064nm and 532nm to meet diverse needs. This device is widely used in medical aesthetics, material analysis, radar ranging, and other fields. With precise parameter adjustment and efficient treatment effects, it provides customized services for medical aesthetic institutions, enhancing customer satisfaction and leading the new trend in precision beauty.

Diode lasers are revolutionizing oral healthcare with their versatile applications. In oral surgery, they enable precise soft tissue cutting with minimal bleeding. In oral medicine, they enhance root canal disinfection and treat dentin hypersensitivity. In orthodontics, they accelerate tooth movement by stimulating bone remodeling. For oral mucosal diseases, low-energy laser irradiation promotes healing. RealLight provides high-performance, cost-effective diode laser modules and systems, driving innovation and efficiency in oral healthcare.

Solid-state lasers play a key role in LIBS (Laser-Induced Breakdown Spectroscopy) technology as an excitation source. Their high energy density, stability, and tunability make them ideal laser sources. By emitting high-energy pulsed laser beams, solid-state lasers excite samples to a high-temperature plasma state, generating radiation spectra for analyzing element types and concentrations. Despite challenges such as power consumption, temperature control, and pulse width, solid-state lasers continue to advance in LIBS applications, as seen in the widespread use of 1535nm erbium glass lasers and 1064nm solid-state lasers. Solid-state lasers demonstrate broad application prospects in fields such as metal material analysis, geological exploration, environmental monitoring, and archaeological research.

The continuous advancement of laser technology has propelled the overall development of the aesthetic medicine industry, significantly improving the precision, safety, and effectiveness of beauty treatments. The introduction of new technologies such as picosecond and femtosecond lasers enables personalized aesthetic treatments by allowing precise parameter adjustments based on different skin types and needs. This facilitates customized treatments, including laser spot removal, hair removal, and skin rejuvenation. With its outstanding laser device performance, RealLight has gained broad market recognition both domestically and internationally. The company has established collaborations with multiple aesthetic institutions, providing professional laser equipment and solutions, further solidifying its position in the industry.